OBT-2024-014
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Obat
BRIN
Biotransformation Product Compounds of artemisinin by the Endophytic Fungus Phomopsis sp. DnAvCw-2: 8-α-Hydroxy Artemisinin for Antimalarial Agent
Direktorat Pemanfaatan Riset dan Inovasi pada Industri
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29 January 2026
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1 mins, 80 words
Kesiapan TRL
Level TRL 6 (Uji Aktivitas Antimalaria)
Bentuk Sediaan
Tablet Salut Selaput
Total Mitra
1 Terdaftar
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0 Poin
Status
Intellectual Property : Registered Patent (2023)
TRL : 3
Research Center : Medicinal Raw Materials and Traditional Medicine
Benefits
Test results show this compound has better antimalarial activity against Plasmodium falciparum 3D7 with an IC50 of 10.7 nM almost 2 times is better than the artemisinin compound as a positive control (18.0 nM) so that this compound can potentially be used as a candidate for antimalarial medicinal ingredients.
Needs
Fermentation technology at a higher scale, to produce more products, further studies are needed so that this compound is safe and effective as an antimalarial medicinal ingredient.